Indications for use, specifying the target Species
The product is indicated for the treatment of nematode or arthropod infestations in horses due to:
Strongylus vulgaris (adults and 4th larval [arterial] stages)
S. edentatus (adults and 4th larval [tissue] stages)
S. equinus (adults)
Triodontophorus spp. (adults)
Adults and immatures (fourth stage larvae) small strongyles or cyathostomes unless otherwise stated. Ivermectin is not effective against the encysted larval stages of the small strongyles.
Lungworms (adult and inhibited fourth stage larvae) Dictyocaulus arnfieldi
Pinworms (adult and inhibited fourth stage larvae) Oxyuris equi
Ascarids (adults and third & fourth stage larvae) Parascaris equorum
Hairworms (adults) Trichostrongylus axei
Large-mouth stomach worms (adults) Habronema muscae
Neck threadworms (microfilariae) Onchocerca spp.
Intestinal threadworms (adults) Strongyloides westeri
Stomach bots (oral and gastric stages) Gasterophilus spp.
Special warnings for each target species
Care should be taken to avoid the following practices because they increase the risk of development of resistance and could ultimately result in ineffective therapy:
Suspected clinical cases of resistance to anthelmintics should be further investigated using appropriate tests (e.g. Faecal Egg Count Reduction Test). Where the results of the tests(s) strongly suggest resistance to a particular anthelmintic, an anthelmintic belonging to another pharmacological class and having a different mode of action should be used.
Resistance to ivermectin has been reported in Parascaris equorum in horses. Therefore, the use of this product should be based on local farm epidemiological information about susceptibility of nematodes and recommendations on how to limit further selection for resistance to anthelmintics.
Special precautions for use
(i) Precautions for use in animals
Special warning for non-target species: The product has been formulated for use in horses only. Cats, Dogs, especially Collies, Old English Sheepdogs and related breed or crosses, and also turtles and tortoises may be adversely affected by the concentration of ivermectin in this product if they are allowed to ingest spilled paste or have access to used syringes.
Parasite resistance to any particular class of anthelmintic may develop following frequent, repeated use of an anthelmintic of that class.
Adverse reactions (frequency and seriousness)
Some horses carrying heavy infection of Onchocerca microfilariae have experienced oedema and pruritus following dosing, assumed to be the result of death of large numbers of microfilariae. These signs resolve within a few days but symptomatic treatment may be advisable.
Use during pregnancy lactation or lay
The safety of the veterinary medicinal product has not been established during pregnancy and lactation. Use only according to risk/benefit analysis by the responsible veterinary surgeon.
Amounts to be administered and administration route
Administer orally as a single dose rate to horses at the recommended dose level of 0.2mg ivermectin per kilogram of bodyweight. Each syringe delivers 120mg ivermectin, sufficient to treat 600kg of bodyweight.
To ensure administration of a correct dose, body weight should be determined as accurately as possible.
If animals are to be treated collectively rather than individually, they should be grouped according to their body weight and dosed accordingly, in order to avoid under- or over-dosing.
This is a single dose product. Discard after use.
Overdose (symptoms, emergency procedures, antidotes), if necessary
Mild transitory signs (slowed pupillary light response and depression) have been seen at a dose of 1.8mg/kg (9 times the recommended dose level). Other signs seen at higher doses includes mydriasis, ataxia, tremors, stupor, coma and death. The less severe signs have been transitory. No antidote has been identified; however, symptomatic therapy may be beneficial.
Meat and offal 34 days.
Do not use in mares producing milk for human consumption.
Link to product Datasheet on NOAH
Link to product Data on VMD product information Database
Link to product datasheet